Cambridge Healthtech Institute’s 2nd Annual

Targeting Transcription Factors

Innovative Chemistries and Assays for Increasing Druggability of Transcription Factors

October 2-3, 2024


Transcription factors (TFs) are proteins with DNA-binding domains and their structure, binding, or activity are often found associated with many abnormalities in cellular function or in disease. There have been efforts to modulate the binding, interactions, activity, or expression levels of TFs to generate the desired biological outcomes. However, their lack of defined structure and binding pockets have made them somewhat “undruggable.” Cambridge Healthtech Institute’s conference on Targeting Transcription Factors brings together scientists who are working on innovative ways to help modulate this very important class of proteins for therapeutic intervention.


Who should attend: Scientist, Team Leader, Vice President, CSO, CEO in Biology, Chemistry, Pharmacology, Target Discovery, Lead Discovery, Drug Design, Computational Biology, Genomics, Assay Development and Screening


Coverage will include, but is not limited to:


  • Progress in targeting transcription factors like myc, p53, STAT, TEAD, IKZF, and more
  • Targeting nuclear receptors, chromatin remodeling complexes, transcriptional activators and more
  • Understanding the structural basis of transcription factor-driven cellular changes
  • Utilizing innovative assays and technologies to modulate transcription factor regulation
  • Chemical biology and protein degradation strategies for targeting transcription factors
  • Development of small molecules and other modalities for drugging transcription factors
  • New screening platforms and models for identifying transcription factor modulators


The deadline for priority consideration is March 8, 2024.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


Opportunities for Participation:



For more details on the conference, please contact:

Tanuja Koppal, PhD

Senior Conference Director

Cambridge Healthtech Institute



For sponsorship information, please contact:

Kristin Skahan

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5431