Cambridge Healthtech Institute’s Inaugural

Targeting Transcription Factors

Innovative Chemistries, Assays, and Modalities for Increasing Druggability

September 27-28, 2023

 

Transcription factors are proteins with DNA-binding domains that are involved in gene transcription. They are key cell regulators and alterations in their structure, binding, or activity are often found associated with many abnormalities in cellular function and in disease. Transcription factors have been targeted in different ways, by modulating their binding, interactions, activity, or expression levels, to generate the desired biological outcomes. However, their lack of defined structure and binding pockets have made them somewhat “undruggable.” Cambridge Healthtech Institute’s conference on Targeting Transcription Factors brings together scientists who are working on innovative ways to help modulate various transcription factors for therapeutic intervention.

 

Who should attend: Scientist in Oncology, Molecular and Cellular Biology, Discovery Biology, Target Discovery, Medicinal Chemistry, Discovery Chemistry, Lead Discovery, Target Identification and Validation, Chemical Biology, Proteomics, Genomics, Assay Development, and Molecular Screening.

 

Coverage will include, but is not limited to:

 

  • Progress in targeting transcription factors like myc, p53, STAT, TEAD, HIF, Nrf2, and more
  • Understanding and targeting nuclear receptors
  • Utilizing innovative technologies to modify transcription factor regulation
  • New chemical biology and protein degradation strategies for targeting transcription factors
  • Development of small molecule inhibitors and activators of transcription factor-driven pathways
  • Understanding the structural basis of transcription factor-related mechanisms
  • New screening platforms and models for identifying transcription factor modulators

 

The deadline for priority consideration is March 17, 2023.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

Opportunities for Participation:

 

 

For more details on the conference, please contact:

Tanuja Koppal, PhD

Senior Conference Director

Cambridge Healthtech Institute

Email: tkoppal@healthtech.com

 

For sponsorship information, please contact:

Kristin Skahan

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5431

Email: kskahan@healthtech.com