Cambridge Healthtech Institute’s 14th Annual

Strategies for Targeting Kinases

Novel Chemistries and Techniques for Studying, Modulating, and Degrading Kinases

September 25, 2023

 

There has been growing interest in targeting kinases such as JAK, TYK, IRAK, SIK, CDK, MEK, ERK, RTK, PLK, PI3K, ALK, MAPK, GSK, LRRK, and more for their role in neurodegeneration, inflammation, cancer, autoimmune, and other disorders. However, targeting kinases selectively and specifically has always been a challenge, as they intersect so many pathways in a cell. Cambridge Healthtech Institute’s symposium on Strategies for Targeting Kinases highlights new assays and tools that are emerging to selectively modify kinases for targeted therapy.

 

Who should attend: Scientist in Oncology, Molecular and Cellular Biology, Discovery Biology, Target Discovery, Medicinal Chemistry, Discovery Chemistry, Lead Discovery, Target Identification and Validation, Chemical Biology, Proteomics, Assay Development, and Molecular Screening.

 

Coverage will include, but is not limited to:

 

  • Using protein degraders for targeting kinases
  • Inhibiting kinases using novel covalent chemistries
  • Biochemical and biophysical tools for protein-protein interactions and binding studies
  • Genomics, proteomics, and imaging tools for kinase inhibitor development
  • Strategies for targeting allosteric sites and non-catalytic functions of kinases
  • Using AI/ML approaches for pursuing “dark” or understudied kinases
  • Computational and MS-based phosphoproteomic profiling for tracking kinase activity
  • Exploring ways to overcome kinase resistance and blood-brain barrier penetration

 

The deadline for priority consideration is March 17, 2023.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

Opportunities for Participation:

 

 

For more details on the conference, please contact:

Tanuja Koppal, PhD

Senior Conference Director

Cambridge Healthtech Institute

Email: tkoppal@healthtech.com

 

For sponsorship information, please contact:

Kristin Skahan

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5431

Email: kskahan@healthtech.com