Cambridge Healthtech Institute’s 18th Annual

GPCR-Based Drug Discovery

Targeting G Protein-Coupled Receptors for New Therapeutic Options

September 26-27, 2023


Cambridge Healthtech Institute's GPCR-Based Drug Discovery conference is now in its 18th year. G protein-coupled receptors (GPCRs), because of their central role in so many cellular processes, are still among the largest class of molecules modulated by biopharmaceutical drugs. The cell surface location of GPCRs enables modulation by a variety of modalities and the ability of each type of receptor to couple to a variety yet specific set of intracellular G proteins provides plenty of complexities for researchers to unravel. This year’s focus will be on case studies of GPCR-targeted compounds for immuno-oncology and other disease areas of emerging GPCR-based therapeutic success. Join us to also learn about new approaches for targeting GPCRs, including rapid new developments in computational methods that are backed by prospective validation.


Who should attend: Biotech/Pharma and Academic Scientists such as: Discovery Biologists, Discovery Pharmacologists, Discovery and Medicinal Chemists, Computational Chemists, Biophysical Scientists, Structural Biologists, Receptor Pharmacologists, Neuroscientists, Translational CNS Researchers.


Coverage will include, but is not limited to:


  • Biophysical tools (NMR, SPR and others) for studying GPCRs
  • DNA-encoded libraries for GPCRs
  • Ubiquitination and targeted degradation of GPCRs
  • cryoEM and structure-based drug design for GPCRs
  • Application of AI and new computational approaches such as virtual ligand screening
  • Allosteric modulators and biased ligands: where are they? 
  • Oral peptides as GPCR protein-protein interaction (PPI)-inhibitors 
  • Novel GPCR signaling and implications for drug discovery


The deadline for priority consideration is March 17, 2023.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


Opportunities for Participation:



For more details on the conference, please contact:

Anjani Shah, PhD

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-247-6252



For sponsorship information, please contact:

Kristin Skahan

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5431