Cambridge Healthtech Institute’s 4th Annual

Lead Generation Strategies

From Many Small-Molecule Hits to Select High-Quality Drug Leads: Applying Biophysical Tools and Other New Approaches

September 17-18, 2020


This conference focuses on how discovery chemists choose which compounds to optimize into drug leads from the many small-molecule compounds that arise from combining newer hit-finding strategies, such as encoded libraries, fragment-based drug design (FBDD), and biophysical screening approaches with classical high-throughput screens. At CHI’s Lead Generation Strategies conference, join drug discovery colleagues from pharma, biotech, and academia to discuss new biophysical techniques and hear case studies on applying orthogonal approaches for converting screening hits to leading drug candidates.


Who should attend: Biophysical Chemists, Medicinal Chemists, Discovery Biologists, Chemical Biologists, Structural Biologists, Computational Chemists in Biotech, Pharma, Academia.


Coverage will include, but is not limited to:                                        

  • Advances in biophysical approaches: SPR, NMR, mass spectrometry, thermal shift assays, microscale thermophoresis, and more
  • Fragment-based lead discovery (FBLD)
  • DNA-encoded libraries
  • Integrating drug leads from various screens
  • Targeted protein degradation strategies for lead generation
  • Protein-protein interactions as drug targets
  • Applying chemical biology and chemoproteomics to drug lead generation


If you would like to submit a proposal to give a presentation at this meeting, please click here.


The deadline for priority consideration is February 26, 2020.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


For more details on the conference, please contact:

Anjani Shah, PhD

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-247-6252



For partnering and sponsorship information, please contact:

Rod Eymael

Manager, Business Development

Cambridge Healthtech Institute

Phone: (+1) 781-247-6286