Cambridge Healthtech Institute’s 5th Annual

Lead Generation Strategies

Integrating New Small Molecule Drug Discovery Approaches

September 29-30, 2021

 

From new chemical entity hit-finding, to selecting which ‘hits’ to focus on, to optimizing the leads into small molecule drug candidates, Cambridge Healthtech Institute’s Lead Generation Strategies conference covers challenges faced in the early steps of new small molecule drug discovery. A particular focus will be on finding compounds with drug-like properties against harder-to-disrupt disease-related proteins such as intracellular signaling complexes or surfaces involved in protein-protein interactions. With newer hit generation strategies such as encoded libraries, fragment-based drug discovery and virtual screening, coupled with advances in biophysical tools and structure-based techniques, questions on how to integrate orthogonal approaches and when to use what, abound. Join fellow ‘small molecule focused' discovery scientists from pharma, biotech and academics to discuss these issues and more. 

 

Who should attend: Medicinal Chemists; Discovery Chemists; Biophysical Chemists; Structural Biologists; Computational Chemists; Discovery Biologists; Directors, Scientists, Principal Scientists, Professors, Post-doctoral Fellows, Graduate Students in departments such as Organic Chemistry, Medicinal Chemistry, Synthetic Chemistry, Biophysics

 

Coverage will include, but is not limited

 

  • Biophysical approaches: SPR, NMR, mass spectrometry, thermal shift assays, microscale thermophoresis and more?
  • Encoded library technology (ELT)
  • Fragment-based lead discovery (FBLD)
  • Integrating drug leads from traditional HTP screens with other screens' leads
  • Targeted protein degradation strategies for lead generation
  • Protein-protein interactions (PPIs) as drug targets
  • Chemical biology and chemo-proteomics applied to drug lead generation
  • Case studies on applying orthogonal approaches

 

If you would like to submit a proposal to give a presentation at this meeting, please click here.

 

The deadline for priority consideration is March 19, 2021.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

For more details on the conference, please contact:

Anjani Shah, PhD

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-247-6252

Email: ashah@healthtech.com

 

For partnering and sponsorship information, please contact:

Rod Eymael

Manager, Business Development

Cambridge Healthtech Institute

Phone: (+1) 781-247-6286

Email: reymael@healthtech.com


Submit a Speaker Proposal