Cambridge Healthtech Institute is pleased to offer skill-based Training Seminars to Discovery on Target. Training Seminars offer in-depth training and instruction on a specific subject area that isn’t covered at this level during the main program, symposia or conference workshops.

Our Training Seminars offer real-life case studies, problems encountered and solutions applied, and extensive coverage of the basic science and academic theory and background. Each Training Seminar offers a mix of formal lectures, interactive discussions and activities to help attendees maximize their learning experiences. These immersive trainings are led by experienced instructors who will focus on content applicable to your current research and provide important guidance to those new to their fields.

TS2: Introduction to Small Molecule Drug Discovery and Development
September 27-28, 2018 | Sheraton Boston

Overall Training Seminar Schedule: 

Day 1 – Thursday | September 27, 2018
12:20 - 2:00 pm Plenary Keynote Program
2:00 - 2:45 pm Refreshment Break in the Exhibit Hall with Poster Viewing
3:00 - 7:00 pm Training Seminar 2 in Session
7:00 pm Training Seminar 2 Close of Day

Day 2 - Friday | September 28, 2018
7:30 - 8:30 am Interactive Breakfast Breakout Discussion Groups
8:30 am - 4:00 pm Training Seminar 2 in Session
12:30 - 1:30 pm Lunch Provided
4:00 pm Training Seminar 2 Concludes

*Training Seminar times include Plenary Keynote Program, Interactive Breakout Discussions, and Exhibit Hall Refreshment Breaks.

About this Training Seminar: 

This 1.5-day lecture-based interactive seminar focuses on strategies for identifying drug discovery targets, discovering and characterizing small molecule hits, and developing structure-activity relationships to advance hits through lead optimization, preclinical development, and clinical evaluation. Participants will learn the stages and processes required to advance programs from idea to clinic, through examples and case studies. This seminar is intended for scientists in either academia or industry who would like to become more familiar with small molecule drug discovery and development.

Topics to be Covered in the Seminar:

  • Stages of drug discovery, development, and clinical evaluation
  • Strategies for identifying key drug discovery targets
  • Screening strategies for discovering and characterizing small molecule modulators
  • Use of structure-based drug design to develop structure-activity relationships
  • In vitro, in culture, and in vivo strategies for optimizing drug-like properties, efficacy and pharmacokinetics
  • Strategies for selecting developmental candidates
  • Requirements for advancing a developmental candidate to clinical trials
  • Biomarkers – translation of efficacy in experimental animals to efficacy in humans
  • Design of clinical trials – proof-of-concept efficacy studies
  • Design of clinical trials – outcome efficacy studies

H. James Harwood Jr., PhD, Founder and CEO, Delphi BioMedical Consultants, LLC

Dr. Harwood is a former Principal Research Investigator at Pfizer. Currently, he is the Founder and Chief Consultant at Delphi BioMedical Consultants LLC, Adjunct Professor Department of Cell and Molecular Biology and Health Professions Advisory Committee Member at the University of Rhode Island, and Adjunct Professor Department of Pathology at Wake Forest University. Jim brings more than 30-year experience in drug R&D in pharmaceutical industry especially in physiology and pharmacology of metabolic and cardiovascular diseases.


September 25 Symposium: Regenerative Medicine
September 25 Short Course 1: Introduction to GPCR-Based Drug Discovery
September 25 Short Course 10: Applications of Artificial Intelligence and Machine Learning in Drug Discovery and Development
September 27-28 Conference: Small Molecules for Cancer Immunotherapy
September 26-27 Training Seminar: Introduction To Small Molecule Drug Discovery And Development
September 27 Short Course 13: GPCR Structure-Based Drug Discovery

Each CHI Training Seminar offers 1.5 Days of instruction with start and stop times for each day shown above and on the Event-at-a-Glance published in the onsite Program & Event Guide. Training Seminars will include morning and afternoon refreshment breaks, as applicable, and lunch will be provided to all registered attendees on the full day of the class.

Each person registered specifically for the Training Seminar will be provided with a hard copy handbook for the Seminar in which they are registered. A limited number of additional handbooks will be available for other delegates who wish to attend the Seminar, but after these have been distributed no additional books will be available.

Though CHI encourages track hopping between conference programs, we ask that Training Seminars not be disturbed once they have begun. In the interest of maintaining the highest quality learning environment for Training Seminar attendees, and because Seminars are conducted differently than conference programming, we ask that attendees commit to attending the entire program, and NOT engaging in track hopping, as to not disturb the hands-on style instruction being offered to the other participants.