Cambridge Healthtech Institute’s 16th Annual

GPCR-Based Drug Discovery

Targeting G Protein-Coupled Receptors for New Therapeutic Options

September 28-29, 2021


Despite being one of the oldest drug-target classes, G Protein-Coupled Receptors (GPCRs) continue to be the focus of new advances in drug discovery. GPCRs initiate many different cellular processes upon activation by hormones, neurotransmitters or other chemical signals. Their cell surface location also makes them easily accessible to a variety of drug-like molecules. Yet GPCRs are a complex drug target because they are embedded in the cell membrane and have intricate signaling patterns via different but specific sets of heterotrimeric G-proteins. Cambridge Healthtech Institue’s GPCR-Based Drug Discovery conference focuses on recent advances that provide insight on GPCR structure and ways to discover or design molecules to modulate them. We will also cover examples of GPCR-targeted drug leads or candidates.


Who should attend: Industry and Academic Discovery Biologists, Structural Biologists, Pharmacologists, Discovery Chemists, Medicinal Chemists, Biophysical Chemists, Computational Chemists, Receptor Pharmacologists, Neuro Pharmacologists, CNS Translational Researchers


Coverage will include, but is not limited


  • Allosteric modulators and biased agonists of GPCRs
  • Biophysical tools (NMR, SPR and others) for studying GPCRs
  • GPCR structural insights from cryo-EM and x-ray crystallography
  • Structure-based design of GPCR-targeted compounds
  • Receptor-ligand binding kinetics and drug discovery implication
  • Case studies of GPCR-targeted compounds
  • GPCRs in cancer
  • GPCR signaling complexities (dimerization, desensitization, receptor recyling, ubiquitination)


If you would like to submit a proposal to give a presentation at this meeting, please click here.


The deadline for priority consideration is March 29, 2021.


All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


For more details on the conference, please contact:

Anjani Shah, PhD

Senior Conference Director

Cambridge Healthtech Institute

Phone: (+1) 781-247-6252



For partnering and sponsorship information, please contact:

Rod Eymael

Manager, Business Development

Cambridge Healthtech Institute

Phone: (+1) 781-247-6286


Submit a Speaker Proposal