DAY 1: 12:20 - 6:30 PM | DAY 2: 7:30 AM - 4:10 PM*

TS3: Introduction to Small Molecule Drug Discovery and Development
North Star


12:20 - 2:00 pm Plenary Keynote Program

2:00 - 2:45 pm Dessert Break in the Exhibit Hall with Poster Viewing

2:45 - 6:30 pm Seminar Sessions

6:30 pm Seminar Close of Day


7:30 - 8:30 am Interactive Breakfast Breakout Discussion Groups

8:40 am - 4:10 pm Seminar Sessions

Lunch also provided.

4:10 pm Seminar Concludes


Exhibit Hall Refreshment Breaks also provided.

*Training Seminar attendees have access to Plenary Keynote Program, Interactive Breakout Discussions, and Exhibit Hall Refreshment Breaks during these times.


H. James Harwood Jr., PhD, Founder and CEO, Delphi BioMedical Consultants, LLC

About This Training Seminar:

This lecture-based interactive seminar focuses on strategies for identifying drug discovery targets, discovering and characterizing small molecule hits, and developing structure-activity relationships to advance hits through lead optimization, preclinical development, and clinical evaluation. Participants will learn the stages and processes required to advance programs from idea to clinic, through examples and case studies. This seminar is intended for scientists in either academia or industry who would like to become more familiar with small molecule drug discovery and development.

What You Will Learn:

  • Stages of drug discovery, development, and clinical evaluation
  • Strategies for identifying key drug discovery targets
  • Screening strategies for discovering and characterizing small molecule modulators
  • Use of structure-based drug design to develop structure-activity relationships
  • In vitro, in culture, and in vivo strategies for optimizing drug-like properties, efficacy and pharmacokinetics
  • Strategies for selecting developmental candidates
  • Requirements for advancing a developmental candidate to clinical trials
  • Biomarkers – translation of efficacy in experimental animals to efficacy in humans
  • Design of clinical trials – proof-of-concept efficacy studies
  • Design of clinical trials – outcome efficacy studies

Instructor Biography:

Harwood_JamesH. James Harwood Jr., PhD, Founder and CEO, Delphi BioMedical Consultants, LLC

Dr. Harwood is a former Principal Research Investigator at Pfizer. Currently, he is the Founder and Chief Consultant at Delphi BioMedical Consultants LLC, Adjunct Professor Department of Cell and Molecular Biology and Health Professions Advisory Committee Member at the University of Rhode Island, and Adjunct Professor Department of Pathology at Wake Forest University. Jim brings more than 30-year experience in drug R&D in the pharmaceutical industry, especially in physiology and pharmacology of metabolic and cardiovascular diseases.


Choose 2 Short Courses and 2 Conferences/Training Seminars
September 16 Pre-Conference Short Course: SC5: Applications of Artificial Intelligence and Machine Learning in Drug Discovery and Development
September 17-18 Training Seminar: TS2: An In-Depth Introduction to Drug Metabolism and Applications to Discovery and Development
September 18 Dinner Short Course: SC8: GPCR Structure-Based Drug Discovery
September 18-19 Training Seminar: TS3: Introduction to Small Molecule Drug Discovery and Development

What is a Training Seminar?

Each CHI Training Seminar offers 1.5 days of instruction with start and stop times for each day shown above and on the Event-at-a-Glance published in the onsite Program & Event Guide. Training Seminars will include morning and afternoon refreshment breaks, as applicable, and lunch will be provided to all registered attendees on the full day of the class.

Each person registered specifically for the Training Seminar will be provided with a hard copy handbook for the seminar in which they are registered. A limited number of additional handbooks will be available for other delegates who wish to attend the seminar, but after these have been distributed, no additional books will be available.

Though CHI encourages track hopping between conference programs, we ask that Training Seminars not be disturbed once they have begun. In the interest of maintaining the highest quality learning environment for Training Seminar attendees, and because seminars are conducted differently than conference programming, we ask that attendees commit to attending the entire program, and not engage in track hopping, as to not disturb the hands-on style instruction being offered to the other participants.