Cambridge Healthtech Institute’s 5th Annual

Small Molecules Targeting RNA

Identifying New Drug Modalities and RNA Moieties for Therapeutic Intervention

September 26-27, 2023

 

Using small molecules to modulate RNA binding and function and get the desired biological outcome has generated much interest in drug discovery. However, understanding the structure and function of various RNA moieties present in the cell and the proteins they interact with-- and then identifying which one to target and how to target it has not been that easy. Challenges also exist in terms of determining the in vivo specificity, selectivity, and safety of these new small molecule modalities. Cambridge Healthtech Institute's conference on Small Molecules Targeting RNA will highlight some of the innovative approaches being pursued to identify and modulate the right RNA target.

 

Who should attend: Scientist in Molecular and Cellular Biology, Discovery Biology, Medicinal Chemistry, Lead Discovery, Drug Design, Computational Biology, Genomics, Assay Development and Screening.     

 

Coverage will include, but is not limited to:

 

  • Tools for identifying the right RNA sequence or regulatory element for therapeutic intervention
  • Targeting pre-mRNA, mRNA, tRNA, and RNA binding proteins
  • Identifying pathways (splicing, translation, transcription) for RNA modulation
  • Designing small molecule libraries specific to RNA
  • Determining the structural and physicochemical constraints for RNA-ligand interactions
  • Strategies for characterization and lead optimization of RNA-targeting small molecules
  • Biophysical/phenotypic screening for identifying and quantifying RNA binding
  • Utilizing artificial intelligence and machine learning for RNA drug discovery
  • Understanding RNA epigenetics
  • Challenges in designing small molecules that bind RNA

 

The deadline for priority consideration is March 17, 2023.

 

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

 

Opportunities for Participation:

 

 

For more details on the conference, please contact:

Tanuja Koppal, PhD

Senior Conference Director

Cambridge Healthtech Institute

Email: tkoppal@healthtech.com

 

For sponsorship information, please contact:

Kristin Skahan

Senior Business Development Manager

Cambridge Healthtech Institute

Phone: (+1) 781-972-5431

Email: kskahan@healthtech.com