Cambridge Healthtech Institute’s 20th Annual

Genomics-Driven Drug Discovery

Utilizing CRISPR Screening, Single-Cell Sequencing, Spatial, and Synthetic Biology

September 27-28, 2023

While finding novel druggable targets and drug modalities for therapeutic intervention remains a top priority for the pharma/biotech industry, identifying and validating "good" targets and leads remains challenging. Cambridge Healthtech Institute’s conference on Genomics-Driven Drug Discovery discusses the use of functional genomics screening, gene editing, single-cell sequencing, spatial analysis, and synthetic biology for applications in drug discovery. Case studies will highlight how CRISPR screening, base editing, single cell RNA sequencing, and spatial transcriptomics are being used to identify cellular pathways and difficult or “undruggable” targets. Complementary use of these genomic technologies with artificial intelligence (AI), machine learning (ML), imaging, 3D organoid models, and more will also be discussed.

Who should attend: Scientist in Molecular and Cellular Biology, Discovery Biology, Target Discovery, Medicinal Chemistry, Discovery Chemistry, Lead Discovery, Target Identification and Validation, Chemical Biology, Genomics, Computational Screening, Assay Development and Screening.

Coverage will include, but is not limited to:

Functional genomics approaches for in vitro and in vivo target screening
Use of single-cell sequencing and analysis for drug discovery
Exploiting spatial biology for understanding cellular interactions
CRISPR and other gene editing-based screening for finding novel targets
Whole transcriptome profiling for expression analysis
Microscopy-based tools like cell painting for genomic/spatial studies
3D organoid models for drug discovery and screening
Using AI/ML to identify, evaluate, and prioritize drug targets and leads
Exploring synthetic biology for drug discovery

The deadline for priority consideration is March 17, 2023.

All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

Opportunities for Participation: