Advances in Gene Editing and Gene Silencing - Part 2 Header


Cambridge Healthtech Institute’s 13th annual two-part conference on Advances in Gene Editing and Gene Silencing will cover the latest in the use of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)/Cas9-based gene editing and RNA interference (RNAi) for use in drug discovery and for developing novel drug therapies.

Part 2 will cover the latest in the use of CRISPR/Cas9 and RNAi for functional screening. It will cover everything from assay design to data analysis when conducting low and high throughput screens and generating cellular models, both in vitro and in vivo, using CRISPR/Cas9, siRNA (small interfering RNA), and shRNA (short hairpin RNA), in a way that will evoke thought-provoking discussions and sharing of best practices. Screening experts from pharma/biotech as well as from academic and government labs will share their experiences leveraging the utility of these diverse screening platforms for a wide range of applications.

Topics will include, but are not limited to:

  • CRISPR versus siRNA/shRNA screens: Pooled versus arrayed screening; Genome-wide versus focused screening
  • Library design, reagent choices and assay platforms, for CRISPR and RNAi screening
  • Complementary use of gene editing and RNAi for functional screening
  • Applications in target discovery and pathway analysis
  • Emerging applications for in vivo and ex vivo models using CRISPR and RNAi
  • Use of advanced screening models: 3D cultures, co-cultures, stem cells and engineered cell systems
  • Tackling challenges with off-target effects, transfection and delivery
  • Overseeing quality control, data analysis and reproducibility

Who should attend: Students, Post-docs, Lab Technicians, Managers, Scientists, Team Leads, Directors and Executives from Pharma, Biotech, Academia, Government, Contract Research Labs and Technology Providers involved in Drug Discovery, Functional Screening, High-throughput screening, Target ID and Validation, Biomarker Discovery, Translational Research, Bioinformatics. Viral Research, Cell and Gene Therapy.

If you are interested in speaking, please click here.

Click here to register for a special early-bird discounted rate.

The deadline for submission is March 4, 2016.

All proposals are subject to review by the Scientific Advisory Committee to ensure the highest quality of the conference program. Please note that due to limited speaking slots, preference is given to pharmaceutical and biotech companies, regulators and those from academia. Additionally, vendors/consultants who provide products and services to these biopharmaceutical companies are offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.

For questions or suggestions about the meeting, please contact:
Tanuja Koppal, Ph.D.
Conference Director
Cambridge Healthtech Institute
E: tkoppal@healthtech.com

For sponsorship and exhibit sales information including sponsored podium presentations, contact:
Jon Stroup
Senior Manager, Business Development
Cambridge Healthtech Institute
T: (+1) 781-972-5483
E: jstroup@healthtech.com