Genome editing is rapidly turning into a tool that promises both specificity and versatility that are important for functional genomics screens. Cambridge Healthtech Institute’s 11th annual conference on Genome Editing for Functional Genomics Screens will bring together experts to try and figure out how and where genome editing can be best applied in functional screening. What are the different tools and reagents that can be used, and based on those choices what are the downstream challenges encountered with assay design and data analysis? What are the strengths and limitations of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) -based screens, when compared to siRNA and shRNA screens? Can some of the lessons learned from the early days of RNAi screening, help with setting up these newer screens? Can advanced cellular models such as, 3D cell cultures, co-cultures and stem cells be used to launch next-generation functional screens. Screening experts from pharma/biotech as well as from academic and government labs will share their experiences leveraging the utility of genome editing for diverse screening platforms and for creating cell lines and models for a wide range of applications. The conference will include oral presentations, posters, interactive panel discussions and technology workshops, where scientists can share strategies and best practices to figure out what works and what doesn’t, under certain conditions.
Topics will include, but are not limited to:
Advances in genome editing tools: CRISPRs, TALENs, ZFNs and more
Understanding CRISPR interference (CRISPRi)
Comparing CRISPR/Cas9 screens to pooled shRNA screens
Setting up high-throughput genome-wide screens
Genome editing for creating relevant cell lines, validating targets
Exploring versatility and use of genome editing
Use of 3D cultures, co-cultures and stem cells models
Tackling false positives and false negatives
Data analysis and hit prioritization
Who should attend:Students, Post-docs, Lab Technicians, Managers, Scientists, Team Leads, Directors and Executives from Pharma, Biotech, Academia, Government, Contract Research Labs and Technology Providers involved in Drug Discovery, Functional Screening, Compound Screening, High-throughput screening, Target ID and validation, Hit-to-Lead Screening, Biomarker Discovery, Translational Research, Safety Screening and Predictive Screening.
If you are interested in speaking, please click here to submit a proposal.
The deadline for submission is April 4, 2014.
All proposals are subject to review by the Scientific Advisory Committee to ensure the highest quality of the conference program. Please note that due to limited speaking slots, preference is given to pharmaceutical and biotech companies, regulators and those from academia. Additionally, vendors/consultants who provide products and services to these biopharmaceutical companies are offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
For questions or suggestions about the meeting, please contact:
Tanuja Koppal, Ph.D.,
Cambridge Healthtech Institute
T: (+1) 973-525-4667
For sponsorship and exhibit sales information including sponsored podium presentations, contact:
Manager, Business Development
Cambridge Healthtech Institute
T: (+1) 781-972-5483