Join us in Boston!
November 2-4, 2011

Thank you to all of our speakers, sponsors, and exhibitors for your support and contribution, and to all the delegates for your participation.
The success of this event is largely due to the dedicated participants that return with us year after year.

If you would like to share your feedback, or give input for next year’s event, please contact Margit Eder at

Discovery on Target 2010

Concurrent Tracks | November 2-3, 2010 

HDAC Inhibitors

GPCR-Based Drug Discovery

Ion Channels as Therapeutic Targets

Targeting the P13K Pathway 

Concurrent Tracks | November 3-4, 2010 

RNAi for Functional Screens
The Challenge of Developing Kinase Inhibitors
Diabetes Drug Discovery
New Ways to Tackle COPD and Other Chronic Pulmonary Diseases 



Allosteric Modulators of GPCRs  

Structure-Based Design of Ion Channel – Linked Receptors   

Best Practices for Setting Up Effective RNAi Screens  

In vivo Discovery and Validation Using RNAi  

Assessing Cardio Safety of Diabetes Drug Candidates  

*Separate registration required. 


Edward Seto, Ph.D. 

Chairman, Department of Molecular Oncology, H. Lee Moffitt Cancer Center 

Gregory J. Kaczorowski, Ph.D. 

Adjunct Professor, Physiology and Pharmacology, New Jersey Medical School; Adjunct Professor, Physiology and Biophysics, Robert Wood Johnson Medical School 

Laszlo Kiss, Ph.D. 

Senior Research Fellow, Merck Research Laboratories 

Spyro Mousses, Ph.D. 

Vice President, Office of Innovation and Director, Center of BioIntelligence, Translational Genomics Research Institute 

Jorge Plutzky, M.D. 

Director, The Vascular Disease Prevention Program, Cardiovascular Division, Brigham and Women’s Hospital and Associate Professor, Harvard Medical School 

Thomas Sakmar, M.D. 

Professor, Molecular Biology and Biochemistry, Rockefeller University 

DOT Hub Icon 

 Short Courses

2015 Discovery on Target Brochure  





Molecular Sensing

Rosa Drug Development Advisors






The exhibit hall was sold out in 2014, so please contact us early to reserve your place. To customize your sponsorship or exhibit package for 2015, contact:

Jon Stroup
Sr. Business Development Manager


September 21 

Next-Generation Histone Deacetylase Inhibitors Symposia 

Strategies for Rare Diseases Symposia 

September 22 

Developing CRISPR-Based Therapies Symposia 

September 22 - 23 

Targeting Epigenetic Readers and Chromatin Remodelers 

Targeting the Ubiquitin Proteasome System 

Targeting the Microbiome 

GPCR - Based Drug Discovery - Part 1 

Antibodies Against Membrane Protein Targets - Part 1 

RNAi for Functional Genomics Screening 

Gene Therapy Breakthroughs 

Targeting Ocular Disorders 

September 23 - 24 

Targeting Histone Methyltransferases and Demethylases 

Targeting the Unfolded Protein Response 

Kinase Inhibitor Discovery 

GPCR-Based Drug Discovery - Part 2 

Antibodies Against Membrane Protein Targets - Part 2 

New Frontiers in Gene Editing 

Quantitative Systems Pharmacology 

Short Courses 

SC1: Cancer Metabolism: Pathways, Targets and Clinical Updates 

SC2: Leveraging Data and Analytics for Drug DiSCovery 

SC3: Setting Up Effective Rnai SCreens: From Design to Data to Validation 

SC4: Phenotypic SCreening and Chemical Probe Development 

SC5: GPCR Structure-based Drug Discovery 

SC6: Targeting of GPCRs with Monoclonal Antibodies 

SC7: Setting Up Effective Functional SCreens Using 3D Cell Cultures 

SC8: Targeting Protein-protein Interactions: Biophysical Approaches 

SC9: Preclinical Animal Models for Ocular Indications 

SC10: Introduction to Allosteric Modulators and Biased Ligands of GPCRs 

SC11: Introduction to Targeted Covalent Inhibitors 

SC12: Assays and High-throughput SCreening for Novel Epigenetic Inhibitors 

SC13: Gamification and Drug Target Challenges 

SC14: A Primer to Gene Editing: Tools and Applications 

SC15: Using Mechanistic Physiological Models In Drug Development